DiaComp Mouse Diet Information

(last updated: February 2010)

Many factors can affect the etiology and pathogenesis of diabetic complications. One such factor is the mouse diet. Depending on the intended research goals, mouse diets can affect not only the experimental etiology of specific diabetic complications but in some cases are required to induce the pathology. Members of the DiaComp use a number of different diets depending on the diabetic complication being studied and specific experimental question being asked. Table 1 presents the consensus of the DiaComp investigators with regard to baseline diets under varying fat concentrations. Table 2 presents all the current diets used by the DiaComp investigators grouped by diabetic complication type.



Table 1. DiaComp Consensus Diets Based on Varying Fat Concentrations


Manufacturer Catalog # Name % Fat % Chol Calories from Fat Source of Fat
LOW FAT LabDiet 5001/5053 Rodent Chow 5001 < 4.5 200 PPM 13.50% Soybean Meal, Porcine Animal Fat
MED FAT LabDiet 5K20 JL Mouse Breeder/Auto 12 270 PPM 27.00% Soybean Oil, Corn Oil
HIGH FAT Harlan Teklad TD 88137 Western 21 0.2 42.00% Anhydrous Milk Fat


Diets can be filtered by Fat Source and Fat Percentage (see Table 1 above). Please select your options below then click the 'Submit' button.


Fat Source
Fat Percentage
PI
Complication

   

Table 2. Mouse Diets used by DiaComp Investigators


ComplicationPIDiet
Manufacturer
Diet Catalog
Number
Diet
Name
% Fat% CholesterolCalories
From Fat
Source of FatUsed to Induce
complication?
Cardiomyopathy & Cardiovascular
Davis, RichardResearch DietsD12079B
Western
21.211.93 kcal/g
Corn Oil, Milk Fat
Yes
Harlan TekladTD 90221
Cocoa Butter Diet with 75% Chow
151.251.14 kCal/g
Cocoa Butter, Fat in Chow
Yes
Schaffer, JeanHarlan TekladTD 88137
Western
210.242%
Anhydrous Milk Fat
No
Abel, E. DaleHarlan Teklad8656
Sterilizable Rodent Diet
40Not Specified
No Added Fat
No
Harlan Teklad3080
Capecchi Breeder Chow
9.60Not Specified
Soybean Oil
No
Research DietsD12451
45% High Fat Diet
24196.5 mg/kg45%
Lard
Yes
Research DietsD12492
60% High Fat Diet
35NS60%
Lard
Yes
BioserveS3888
Doxycycline Chow
8.6NSNS
Animal Fat, Soybean Oil
Yes
Goldberg, IraDyets102581
Fish Oil 102581
NSNS9 kcal/g
Corn Oil, Fish Oil
 
Dyets180538
Menhaden Oil 180538
NSNS9 kcal/g
Corn Oil, Menhaden Oil
 
Harlan TekladTD 88137
Western
210.242%
Anhydrous Milk Fat
 
Research DietsD12450B
Rodent Diet with 10% kcal% fat
4.3180 kcal
Lard, Soybean Oil
 
Research DietsD12492
60% High Fat Diet
35NS60%
Lard
 
Research DietsC13002
Paigen Diet
7.51.25
Cocoa Butter
 
Maeda, NobuyoLab DietRMH3000 5P76
Prolab Isopro RMH 3000
5195 PPM14%
Animal Fat, Soybean Oil
 
Harlan TekladTD 88137
Western
210.242%
Anhydrous Milk Fat
Yes
Nephropathy
Brosius, FrankLab Diet5001
Rodent Chow 5001
< 4.5200 PPM13.5%
Porcine Animal Fat, Soybean Meal
No
Lab Diet5008
Rodent Chow 5008
< 4.5280 PPM16.71%
Porcine Animal Fat, Soybean Meal
No
Harris, RaymondLab Diet5001
Rodent Diet 5001
< 4.5200 PPM13.5%
Porcine Animal Fat
No
Calcutt, Nigel5001
PMI Rodent Diet
5200 PPM12%
Animal Fat
No
Research DietsD12450B
Rodent Diet with 10% kcal% fat
4.3NS10%
Lard, Soybean Oil
No
Levi, MosheHarlan Teklad2018
Teklad Global 18% Protein Rodent Diet
6NS17%
Crude Oil
 
Harlan TekladTD 88137
Western
210.242%
Anhydrous Milk Fat
 
Lab Diet5K20
JL Mouse Breeder/Auto
12270 PPM27%
Corn Oil, Soybean Oil
 
Lab Diet5K52/5K67
JL Rat and Mouse /Auto 6F
7240 PPM16%
Soybean Oil
 
Research DietsD12329
Surwit Diet 11 kcal% Fat w/sucrose
5NS11%
Coconut Oil, Soybean Oil
 
Research DietsD12331
Surwit Diet 58 kcal% Fat w/sucrose
36NS58%
Coconut Oil, Soybean Oil
 
Research DietsD12450B
Rodent Diet with 10% kcal% fat
4.3NS10%
Lard, Soybean Oil
 
Research DietsD12492
60% High Fat Diet
35NS60%
Lard
 
Smithies, OliverLab DietRMH3000 5P76
Prolab Isopro RMH 3000
5195 PPM14%
Animal Fat, Soybean Oil
 
Harlan TekladTD 88137
Western
210.242%
Anhydrous Milk Fat
Yes
Sharma, KumarResearch DietsD12492
60% High Fat Diet
35NS60%
Lard
Yes
Coffman, ThomasLab Diet5001
Rodent Chow 5001
4.5200 PPM13.5%
Porcine Animal Fat, Soybean Meal
 
Lab Diet5015
Rodent Chow 5015
110.002825.4%
 
Neuropathy
Calcutt, NigelResearch DietsD12492
60% High Fat Diet
35NS60%
Lard
Yes
Feldman, EvaLab Diet5053
Pico Lab Rodent Diet 20
5141 PPM13.2%
Soybean Oil
No
Research DietsD12541
45% High Fat Diet
24196.5 mg/kg45%
Lard, Soybean Oil
Yes
Research DietsD10001
AIN-76A
5NS11.5%
Corn Oil
No
Baumann, ThomasLab Diet5001
Rodent Chow 5001
4.5200 PPM13.5%
Porcine Animal Fat, Soybean Meal
No
Lab Diet5015
Rodent Chow 5015
110.002825.4%
No
Retinopathy
Barber, AlistairHarlan Teklad2019
Protein Rodent Diet
9NSNS
Crude Oil
No
Smith, NadineLab Diet5001
Rodent Chow 5001
5200 PPM13.5%
Porcine Animal Fat
No