Elevated plasma cyclic guanosine monophosphate may explain greater efferent
arteriolar tone in adults with longstanding type 1 diabetes: A brief report.
Authors Bjornstad P, Lovshin JA, Lytvyn Y, Lovblom LE, Scarr D, Boulet G, Farooqi MA,
Orszag A, Bai JW, Weisman A, Keenan HA, Brent MH, Paul N, Bril V, Perkins BA,
Cherney DZI
Submitted By Petter Bjornstad on 8/19/2019
Status Published
Journal Journal of diabetes and its complications
Year 2019
Date Published 8/1/2019
Volume : Pages 33 : 547 - 549
PubMed Reference 31186164
Abstract Cyclic guanosine monophosphate (cGMP) influences intrarenal hemodynamics in
animal models, but the relationship between cGMP and renal function in adults
with type 1 diabetes (T1D) remains unclear. In this study, plasma cGMP
correlated with efferent arteriolar resistance, effective renal plasma flow, and
renal vascular resistance in adults with T1D.