a-Lipoic acid protects diabetic apolipoprotein E-deficient mice from
Authors Yi X, Nickeleit V, James LR, Maeda N
Submitted By Nobuyo Maeda on 5/2/2011
Status Published
Journal Journal of diabetes and its complications
Year 2011
Date Published 10/1/2010
Volume : Pages 25 : 193 - 201
PubMed Reference 20801062
Abstract Both hyperglycemia and hyperlipidemia increase oxidative stress and contribute
to the development of diabetic nephropathy (DN). We investigated the effects of
a-lipoic acid, a natural antioxidant and a cofactor in the multienzyme
complexes, on the development of DN in diabetic apolipoprotein E-deficient mice.

Investigators with authorship
Nobuyo MaedaUniversity of North Carolina