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Susceptible mice: identifying a diabetic nephropathy disease locus using a
Frank Brosius on 5/2/2011
Volume : Pages
78 : 431 - 432
Diabetic nephropathy is a common, complex disease with a clear genetic
predisposition. Human gene association studies are beginning to bear fruit by
identifying gene loci that increase diabetic nephropathy risk. Chua et al.
report a similar study in diabetic mice that reveals a major nephropathy locus
on chromosome 8. Could this be a human nephropathy gene? Time will tell, but
such findings will at least improve the use of mouse models of human kidney
Investigators with authorship
University of Arizona
Neuropathy & Neurocognition
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Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:
Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255
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