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Publication

Histologic changes in diabetic gastroparesis.

Authors Farrugia G Submitted By Gianrico Farrugia on 5/10/2015 Status Published Journal Gastroenterology clinics of North America Year 2015 Date Published 3/1/2015 Volume : Pages 44 : 31 - 38 PubMed Reference 25667021 Abstract The cellular abnormalities that lead to diabetic gastroparesis are increasingly being understood. Several key cell types are affected by diabetes, leading to gastroparesis. These changes include abnormalities in the extrinsic innervation to the stomach, loss of key neurotransmitters at the level of the enteric nervous system, smooth muscle abnormalities, loss of interstitial cells of Cajal, and changes in the macrophage population resident in the muscle wall. This article reviews the current understanding with a focus on data from human studies when available.

Investigators with authorship
Name Institution Gianrico Farrugia Mayo Clinic Rochester

Complications
All Complications Bioinformatics Bone Cardiomyopathy Cardiovascular Gastro-Intestinal (GI) Nephropathy Neuropathy & Neurocognition Pediatric Endocrinology Retinopathy Uropathy Wound Healing