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Publication

Lipolysis, and Not Hepatic Lipogenesis, Is the Primary Modulator of Triglyceride Levels in Streptozotocin-Induced Diabetic Mice.

Authors Willecke F, Scerbo D, Nagareddy P, Obunike JC, Barrett TJ, Abdillahi ML, Trent CM, Huggins LA, Fisher EA, Drosatos K, Goldberg IJ Submitted By Ira Goldberg on 12/8/2014 Status Published Journal Arteriosclerosis, thrombosis, and vascular biology Year 2014 Date Published 11/13/2014 Volume : Pages 35 : 102 - 110 PubMed Reference 25395613 Abstract Diabetic hypertriglyceridemia is thought to be primarily driven by increased hepatic de novo lipogenesis. However, experiments in animal models indicated that insulin deficiency should decrease hepatic de novo lipogenesis and reduce plasma triglyceride levels.

Investigators with authorship
Name Institution Edward Fisher New York University School of Medicine Ira Goldberg New York University School of Medicine

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