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Retinal ganglion cells in diabetes.
Kern TS, Barber AJ
Alistair Barber on 4/15/2014
The Journal of physiology
Volume : Pages
586 : 4401 - 4408
Diabetic retinopathy has long been recognized as a vascular disease that
develops in most patients, and it was believed that the visual dysfunction that
develops in some diabetics was due to the vascular lesions used to characterize
the disease. It is becoming increasingly clear that neuronal cells of the retina
also are affected by diabetes, resulting in dysfunction and even degeneration of
some neuronal cells. Retinal ganglion cells (RGCs) are the best studied of the
retinal neurons with respect to the effect of diabetes. Although investigations
are providing new information about RGCs in diabetes, including therapies to
inhibit the neurodegeneration, critical information about the function, anatomy
and response properties of these cells is yet needed to understand the
relationship between RGC changes and visual dysfunction in diabetes.
Investigators with authorship
Pennsylvania State University-Penn State College of Medicine
Neuropathy & Neurocognition
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Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:
Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255
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