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An integrated approach to diabetic retinopathy research.
Gardner TW, Abcouwer SF, Barber AJ, Jackson GR
Submitted Externally on 4/15/2014
Archives of ophthalmology
Volume : Pages
129 : 230 - 235
This review discusses the pathophysiology of diabetic retinopathy related to
direct effects of loss of insulin receptor action and metabolic dysregulation on
the retina. The resulting sensory neuropathy can be diagnosed by structural and
functional tests in patients with mild nonproliferative diabetic retinopathy.
Research teams can collaborate to integrate ocular and systemic factors that
impair vision and to design strategies to maintain retinal function in persons
with diabetes mellitus. Evolving concepts may lead to inclusion of tests of
retinal function in the detection of diabetic retinopathy and neuroprotective
strategies to preserve vision for persons with diabetes.
Investigators with authorship
University of Michigan-Ann Arbor
Pennsylvania State University-Penn State College of Medicine
Neuropathy & Neurocognition
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Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:
Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255
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