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Integrating genetic and gene expression data to study the metabolic syndrome and
diabetes in mice.
Drake TA, Schadt EE, Davis RC, Lusis AJ
Richard Davis on 2/11/2009
American journal of therapeutics
Volume : Pages
12(6) : 503 - 511
Increasingly, the mouse is becoming the standard model for mammalian physiology
and disease. It can be genetically analyzed and manipulated with relative ease.
Moreover, the endogenous genetic variation that exists among inbred mouse
strains can be exploited to identify genetic control of complex physiologic
processes involved in diabetes and the metabolic syndrome, among other
conditions relevant to human disease. Recent advances in genetics and gene
expression technology have greatly increased the knowledge to be derived from
this approach when applied to traditional genetic studies.
Investigators with authorship
University of California Los Angeles
Neuropathy & Neurocognition
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Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:
Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255
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