Toward a Mouse Model of Diabetic Nephropathy: Is Endothelial Nitric Oxide
Synthase the Missing Link?
Authors Quagin, SE Coffman, TM
Submitted By Thomas Coffman on 2/9/2009
Status Published
Journal Journal of the American Society of Nephrology : JASN
Year 2007
Date Published 2/1/2007
Volume : Pages 18 : 364 - 366
PubMed Reference 17259594
Abstract Two articles in the October and February issues of JASN reported that diabetic
mice that lack the eNOS gene develop accelerated kidney disease with features
that resemble human diabetic nephropathy (DN). These articles are significant
given the lack of good mouse models to study this important clinical issue.

Investigators with authorship
Thomas CoffmanDuke University Medical Center