BALB/C-Tbxa2rtm1Cof

BALB/C mouse where the thromboxane A2 receptor gene has been knocked out. The insertion of a PGK-neo cassette into exon 2 disrupted sequence encoding the third transmembrane domain. Though Northern blot analysis identified several aberrant transcripts in homozygous mutant mice, no normal transcript was detected. Binding assays using a labeled thromboxane agonist indicated an absence of functional receptors in both thymocytes and renal sections obtained from homozygous mutant mice


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Data (.csv filetype)

W rodent (g)

SeriesSexNAvgSD
BALB/C-Tbxa2rtm1CofBoth4828.372.70
 Male4828.372.70
Avg = 29.29
Std = 2.41
N = 12
Age = 24 Avg = 28.48
Std = 2.82
N = 12
Age = 20 Avg = 28.01
Std = 2.87
N = 12
Age = 14 Avg = 27.7
Std = 2.39
N = 12
Age = 10 Avg = 29.29
Std = 2.41
N = 12
Age = 24 Avg = 28.48
Std = 2.82
N = 12
Age = 20 Avg = 28.01
Std = 2.87
N = 12
Age = 14 Avg = 27.7
Std = 2.39
N = 12
Age = 10